I like to ask my students where do you think all those people went to the bathroom during, say Hamlet which is a 3.5 hour play? And when? - no intermissions. The Globe held over a 1000 people, a good percentage of them standing on the floor in what must have been a very rowdy group, given the locale of all in the theatres in the pub & red light district of Bankside London.
Shakespeare was a very popular playwright.